According to the Xinhua News Agency in London, a recent research report published by the British "Nature-Medical" magazine said that American researchers have developed a new type of tuberculosis vaccine, and animal experiments have shown that it is better than the existing BCG vaccine. Researchers at the Einstein College of Medicine in the United States have developed this new vaccine through bacterial genetic modification and named it IKEPLUS. Pulmonary tuberculosis is caused by Mycobacterium tuberculosis, which has a "relative" called Mycobacterium smegmatis, and they all have a gene called esx-3. The researchers found that if the gene in M. smegmatis was removed and the same gene from M. tuberculosis was implanted, the resulting bacteria could be used as a vaccine. Animal experiments show that under the same infection with Mycobacterium tuberculosis, the average survival time of experimental mice without any vaccine was 54 days, and the average survival time of experimental mice injected with BCG vaccine was 65 days. Survival time is up to 135 days. Professor William Jacobs, who led the research, said that the new vaccine's principle of action is different from the existing tuberculosis vaccine. Experiments show that it is better than the BCG vaccine. Researchers will develop a vaccine that can be used in humans on this basis. . (Reporter Huang Kun)
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