China's first ankle joint 3D print implant surgery successfully eighty-year-old Aber turned "future warrior"

According to doctors, combined with 3D printing technology , it is increasingly possible to “tailor-made” personalized surgical solutions for patients to achieve low-cost and high-efficiency treatment effects. Currently, 3D printing technologies such as pelvic fractures are being tried. How much did the surgery cost? The doctor said that because of the experimental stage, it is not good to say the price.

Huang Bo’s family, Mr. Yu, said, “The surgery cost a total of more than 40,000 yuan. After deducting medical insurance and other expenses, we have spent more than 10,000 yuan.”

The metal objects implanted in the future warrior body make it more powerful! Yesterday, this year's 86-year-old Huang Bo, Liwan District, Guangzhou City, really felt the benefits of the "Future Warrior" film. He implanted a titanium metal ankle a year ago to make him move freely, and even "walking like a fly", "I didn't expect one When you are old, you can walk like this!" As soon as he said this, Huang Bo smiled and closed his mouth. According to the hospital, Huang Bo, who has recovered, is the first beneficiary of the application of 3D printing technology in the treatment of chronic osteomyelitis of the ankle.

Today: walking freely and taking care of yourself

“I am able to move around again.” The 86-year-old Huang Bo from Liwan District, Guangzhou City, took a wheelchair to the Third Affiliated Hospital of Guangzhou Medical University for a follow-up examination. “It has been more than a year since I implanted titanium pedals. Walking freely." Speaking, Huang Bo walked down from the wheelchair. Between the actions, it was difficult for everyone to notice that he was already 86 years old.

Huang Bo’s family said, “Huang Bo’s legs are not only flexible, but they can still take care of themselves.”

I used to think about sawing broken legs.

However, Huang Bo’s past is not so optimistic.

"At that time, I thought about cutting off the sick right leg." Mr. Yu, a member of the Huang Bo family, said that during the "Cultural Revolution", Huang Bo had a serious eczema on his right ankle and went to a hospital for radiation therapy. After the radiation treatment such as laser, Huang Bo produced sequelae. In the past 10 years, Huang Bozhen has been hospitalized in several hospitals. He has been treated with metastatic flaps and has never seen the expected effect.

"Some hospital doctors even proposed to cut off the right leg ankle of Huang Bo's illness," Mr. Yu said. "But Huang Bo is so old, it is difficult to live after sawing a broken leg, very cruel!"

Try 3D printing technology therapy

In March 2014, with the mentality of trying it out, Huang Bo went to the Department of Orthopaedics, the Third Affiliated Hospital of Guangzhou Medical University.

The deputy chief physician of Zeng Yidong, who was admitted to the clinic, found that Huang Bo had a chronic osteomyelitis lesion on the entire medial ankle joint, which was the root cause of his repeated ulceration. Clinically, the treatment of osteomyelitis has the characteristics of repeatability and slow onset of action. Once the treatment is not good, the affected limb will face the risk of amputation.

The hospital's Department of Orthopaedics II team repeatedly studied that the traditional method of treatment will form a certain degree of damage to the ankle joint structure, the patient's simple walking after surgery will be seriously affected, can not meet the most basic requirements of patients, and finally confirmed the combination of 3D Printing technology for treatment options.

Mr. Yu said that the doctor told us that there are already successful precedents in foreign countries. "Since foreign countries have advanced 3D printing technology, we are willing to try."

Zeng Yidong said that the treatment of chronic osteomyelitis in Huang Bo's ankle is divided into two stages: the first stage of surgery to remove osteomyelitis lesions, using 3D printing technology to create a bone cement skeleton scaffold identical to the removal of bone lesions, as a temporary placeholder To maintain the space of the bone around the lesion and the relative stability of the ankle joint, to preserve the patient's simple walking function, and to verify the feasibility of the final surgical approach. In the second stage, 3D printing technology was used again to print a titanium skeleton with a 1:1 ratio to the bone being removed and re-implanted into the patient's ankle to achieve a permanent treatment.

Previous: First print the plastic skeleton model

According to the CT examination, the doctors team of the Second Department of Orthopaedics of the hospital first obtained the three-dimensional data of the skeleton of the lesion. After the data processing by the 3D printing company, the 3D printer of high precision was used to print the plastic skeleton model identical to the skeleton of the patient's lesion. Replace the plastic model of the bracket. Perform an in vitro surgical simulation. Determine the specific location and area of ​​the bone to be resected, and estimate the problems that may be encountered during the operation, and further evaluate the feasibility of the surgical plan. At the same time, the anti-reverse mold is carried out by the bracket model to produce a high-precision mold that can be autoclaved and adapted to the needs of the operation. The mold was filled with antibiotic bone cement during the operation to obtain an antibiotic bone cement skeleton.

By using the antibiotic bone cement skeleton scaffold as a placeholder, the doctor temporarily replaces the patient's diseased bone to eliminate the lesion and maintain the ankle joint relatively stable.

Late: implanted titanium skeleton bracket

After nearly 10 months of rehabilitation, Huang Bo's chronic osteomyelitis lesions completely disappeared, and Huang Bo was able to walk on the ground with a walking stick. However, the bone cement skeleton stent is temporary, and how to achieve a permanent effect is the key to the success of long-term treatment of the osteoarthritis of the ovarian joint. Given the growth and healing of muscles and bones after surgery, determining the accuracy of permanent bone scaffolds is the biggest challenge.

After research, the Department of Orthopaedics and the Second District selected a permanent bone scaffold made of titanium with good compatibility with human tissue and internationally accepted. And the accuracy of the titanium skeleton support is determined to be 0.04 mm, because this value is the pore size of the micropores on the surface of the human bone, and is well compatible with the bone tissue of the human body. Subsequently, a new titanium skeleton support was printed in accordance with the three-dimensional design of the bone skeleton support. In January 2015, Huang Bo underwent a second-stage operation, replacing the bone cement skeleton stent placed 10 months ago with a titanium skeleton bracket and re-fixing it. The operation was a complete success.

Dissimilarity: material is almost the same as steel

After half a year of rehabilitation, now, Huang Bo’s ankle has basically recovered, and the condition of ulcers and exudates no longer appears. After a doctor's review, the 3D printed titanium skeleton support at the ankle of Huang Bo is stable in vivo and biocompatible.

Zeng Yidong said, "The implanted titanium skeleton support and the steel plate belong to the same material, and there is no dissimilarity." Huang Bo told reporters, "Even if it is windy or rainy, there is no feeling of rheumatism."

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